I think this is great.
I stumbled across it while searching for the Michael Kupperman TV Funhouse cartoon "Big Boobs Einstein." I've established that I think that Michael Kupperman is the funniest dude in comics, for his sense of absurdism- his Snake And Bacon's Cartoon Cabaret book is amazing. It is maybe too unrelentingly ridiculous for most people- it's not character-based comedy at all, there's nothing to really ground it. I found that cartoon later, somewhere other than Youtube, but this is better. It's made with Julie Klausner, who I had heard about due to her comedy show in New York with Jackie Clarke, Obsessed, probably when I heard that Tom Scharpling had done it once. There are other Julie and Jackie shorts on Youtube, and I think they're great. The video of the live performances don't work so well for me, but I can't even really watch live performances by bands on Youtube. The short film format is great, well-suited for parodies of videos made by soap opera actresses.
They're really funny- as two-woman sketch comedy duos go, I'd put them above the L.A.-based Clifford And Kidd, who came to my attention from their talking about candy bars, which is the type of thing that makes me pay attention to people.
Also from L.A., I like the videos made by Neil Campbell and Paul Rust. Neil Campbell also does a comic strip, found online, called My Naked Dad, that is intermittently funny. Rather than link to that, I will instead point to when his blog had an entry I thought was great.
This post was edited because I got a name wrong, in a way that bothered me, because the name I said that was wrong belongs to a person I don't think is very funny.